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American Society of Microbiology ABMM Sample Questions (Q116-Q121):

NEW QUESTION # 116
An immunocompromised patient develops a disseminated fungal infection. Blood cultures are consistently negative. However, a serum beta-D-glucan assay is markedly elevated. Tissue biopsy reveals the presence of hyaline, septate hyphae with dichotomous branching. The MOST likely causative organism is:

A. Cryptococcus neoformans
B. Rhizopus species
C. Aspergillus fumigatus
D. Mucor species

Answer: C

NEW QUESTION # 117
A patient with a history of travel to a rural area develops a febrile illness with myalgias and thrombocytopenia. Laboratory testing reveals the presence of morulae within circulating leukocytes. The MOST likely diagnosis is:

A. Anaplasmosis
B. Lyme disease
C. Ehrlichiosis
D. Babesiosis

Answer: C

NEW QUESTION # 118
During an outbreak of norovirus gastroenteritis in a nursing home, environmental swabs are collected to identify the source of the infection. Which of the following methods would be MOST appropriate for detecting norovirus in these samples?

A. Reverse transcription-polymerase chain reaction (RT-PCR)
B. Gram staining and microscopy
C. Enzyme-linked immunosorbent assay (ELISA) for viral antigens
D. Culture on human embryonic kidney (HEK) cells

Answer: A

NEW QUESTION # 119
A clinical microbiology laboratory is monitoring the emergence of antimicrobial resistance. The detection of a bacterial isolate with reduced susceptibility to multiple classes of antibiotics, often due to horizontal gene transfer of resistance determinants, is characteristic of:

A. A pan-susceptible organism.
B. A multidrug-resistant (MDR) organism.
C. A naturally competent organism.
D. An intrinsically resistant organism.

Answer: B

NEW QUESTION # 120
A patient presents with a chronic cough, weight loss, and night sweats. Chest X-ray shows cavitarylesions in the upper lobes. Sputum is acid-fast positive. Drug susceptibility testing reveals resistance to isoniazid but susceptibility to rifampin, ethambutol, and pyrazinamide. The MOST appropriate treatment regimen should include:

A. Isoniazid and rifampin
B. Isoniazid, ethambutol, and pyrazinamide
C. Rifampin, ethambutol, and pyrazinamide
D. Isoniazid, rifampin, pyrazinamide, and ethambutol

Answer: C

NEW QUESTION # 121
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